Roux starts for Ireland
There are five personnel changes to the team that claimed an historic 26-20 win over South Africa last weekend and a further five new faces among the replacements.
Hooker Rory Best captains the side for the 11th time and is joined in the front row by Jack McGrath and Tadhg Furlong, who comes in for his first international start at tighthead, while Devin Toner is partnered in the second row by debutant Quinn Roux from Connacht.
Iain Henderson switches to the blindside flank, taking over from the suspended CJ Stander, and Rhys Ruddock comes in at openside for his first start since November 2014, with vice-captain Jamie Heaslip at No.8.
Conor Murray and Paddy Jackson are retained at halfback, while Robbie Henshaw is joined in the centre by Ulster's Stuart Olding, who is set for his first start since his debut against the USA three years ago. Henshaw also made his international bow that night in Houston.
Craig Gilroy is introduced on the left wing for his eighth cap, making it an all-Ulster back-three alongside Andrew Trimble and fullback Jared Payne.
Sean Reidy and Tiernan O'Halloran are the two uncapped players on the bench and they are joined by Richardt Strauss, Dave Kilcoyne, Finlay Bealham, Donnacha Ryan, Kieran Marmion and Ian Madigan.
Ireand: 15 Jared Payne, 14 Andrew Trimble, 13 Robbie Henshaw, 12 Stuart Olding, 11 Craig Gilroy, 10 Paddy Jackson, 9 Conor Murray, 8 Jamie Heaslip, 7 Rhys Ruddock, 6 Iain Henderson, 5 Quinn Roux, 4 Devin Toner, 3 Tadhg Furlong, 2 Rory Best (captain), 1 Jack McGrath.
Replacements: 16 Richardt Strauss, 17 Dave Kilcoyne, 18 Finlay Bealham, 19 Donnacha Ryan, 20 Sean Reidy, 21. Kieran Marmion, 22 Ian Madigan, 23 Tiernan O'Halloran.
Date: Saturday, June 18
Venue: Ellis Park, Johannesburg
Kick-off: 17.00 (16.00 IST; 15.00 GMT)
Referee: Angus Gardner (Australia)
Assistant referees: Glen Jackson (New Zealand), Ben Whitehouse (Wales)
TMO: Jim Yuille (Scotland)
