Wales lose key duo as All Blacks loom
Fullback Liam Williams sustained an abdominal injury, while wing Alex Cuthbert picked up a calf injury during Wales' hard-fought 13-6 win over Georgia.
Williams will also miss the final Test against South Africa due to his commitment with Premiership side the Saracens.
The Wales Rugby Union's statement didn't stipulate the recovery period for the two.
"No time frame for recovery has been set for either player and they have been released back to their respective club/region,"
Prop Samson Lee is highly unlikely to feature due to an Achilles injury.
While flank Justin Tipuric is back in training.