Du Preez hands son the No.10 jumper
The flyhalf, who joined the Sharks from Stormers and Western Province, has been given the nod ahead of young prodigy Curwin Bosch.
Completing the halfback pairing is scrumhalf Cameron White. The 23-year-old takes the place of injured Springbok Louis Schreuder, who suffered a hamstring injury in his side's 31-14 win over the Bulls in a pre-season match in Polokwane last weekend.
While captain Ruan Botha has retained the captain's armband.
The Hong Kong trip will be the Sharks' final preparation match before the start of Super Rugby.
The Sharks start their Super Rugby campaign against the Lions at Ellis Park on February 17.
Sharks: 15 Lwazi Mvovo, 14 Kobus van Wyk, 13 Lukhanho Am, 12 Marius Louw, 11 Makazole Mapimpi, 10 Robert du Preez, 9 Cameron Wright, 8 Keegan Daniel, 7 Jacques Vermeulen, 6 Philip van der Walt, 5 Stephan Lewies, 4 Ruan Botha (captain), 3 Thomas du Toit, 2 Franco Marais, 1 Juan Schoeman.
Replacements: 16 Chiliboy Ralepelle, 17 Mzamo Majola, 18 John-Hubert Meyer, 19 Hyron Andrews, 20 Tyler Paul, 21 Lubabalo “Tera” Mtembu, 22 Grant Williams, 23 Curwin Bosch, 24 Jeremy Ward, 25 Sbusiso Nkosi, 26 Garth April
Date: Saturday, February 3
Venue: Aberdeen Sports Ground, Hong Kong
Kick-Off: 16.00 (08.00 GMT, 10.00 SA Time)
Referee: Tim Baker (Hong Kong)
Assistant referees: Lawrence Wilkinson (Hong Kong), Mark Jackson (Hong Kong)