Foley blow for Waratahs
Foley was named in the starting line-up for this weekend's with head coach Daryl Gibson giving him as much time as possible to get himself fit.
"Bernard hasn't met our 'return to play' protocols so will miss round one.
"While he has been improving daily since last Thursday's game, he's not 100 percent fit to play and we certainly won't be taking any risks.
"He will be with us in South Africa and we have confidence he'll be ready for Round Two.
"Bryce Hegarty will step into the No.10 position nicely for us this weekend.
"He has the experience with 34 Super Rugby games to his name and has been training well on his comeback from injury last year," said Gibson.
Ned Hannigan has also been ruled out due to a minor hamstring strain.
Waratahs: 15 Andrew Kellaway, 14 Reece Robinson, 13 Israel Folau, 12 Irae Simone, 11 Rob Horne, 10 Bryce Hegarty, 9 Nick Phipps, 8 Michael Wells, 7 Michael Hooper (captain), 6 Jack Dempsey, 5 Will Skelton, 4 Dean Mumm, 3 Sekope Kepu, 2 Tolu Latu, 1 Tom Robertson.
Replacements: 16 Hugh Roach, 17 Paddy Ryan, 18 David Lolohea, 19 David McDuling, 20 Brad Wilkin, 21 Matt Lucas, 22 David Horwitz, 23 Taqele Naiyaravoro.
Date: Saturday, February 25
Venue: Allianz Stadium, Sydney
Kick-off: 19.45 (16.45 AWST; 08.45 GMT)
Referee: Ben O'Keeffe (New Zealand)
Assistant referees: Angus Gardner (Australia), Will Houston (Australia)
TMO: Ian Smith (Australia)