Scott's Six Nations all over
Scott suffered ligament damage while playing for club side Edinburgh against Irish province Connacht in the Celtic League last Friday.
"An MRI scan at Spire Murrayfield Hospital confirmed that Scott sustained elbow ligament damage in his club's Pro12 loss to Connacht on Friday," the Scottish Rugby Union said.
"Further examination this Friday will confirm if the player requires surgery on the joint.
"However, it is clear at this stage that he will at least miss the remainder of the 2016 Six Nations, and will return to his club for ongoing care and assessment."
Scott started Scotland's Six Nations-opening defeat by England at Murrayfield last month, but Mark Bennett and Duncan Taylor were in midfield when the team beat Italy 36-20 in Rome last time out.
Scotland will aim for back-to-back wins when France come to Murrayfield on Sunday before concluding their Six Nations campaign against Ireland in Dublin on March 19.
Agence France-Presse