Trinh-Duc starts as France change six
The Montpellier No.10 is one of six changes to the French side from the team that lost to Wales, as he comes in for Jules Plisson, who drops to the bench.
Elsewhere in the backline a fit-again Wesley Fofana is named on the wing in place of Djibril Camara, while Scott Spedding gets the nod at fullback as Maxime Médard drops to the bench.
Finally Gaël Fickou is back in the starting lineup alongside Maxime Mermoz, with Jonathan Danty left out after starting the first three games of the Championship. The other changes come in the pack where Yoann Maestri is restored to the starting line-up after coming off the bench in Cardiff, while Yacouba Camara replaces the injured Antoine Burban.
On the bench there is just one new face, Sébastien Vahaamahina set for his first appearance in this year's Championship.
The returning Spedding, who has yet to feature in this year's competition, admits Scotland will provide a stern test for Les Bleus, even if France have won 10 in a row against the Scots.
"They easily beat Italy whereas we had a lot of trouble beating them. It will be a difficult match. We saw during the World Cup that Scotland could easily have made the semi-final. I don't think it will be an easy match and we're taking it very seriously.
"They have some very dangerous players like [Stuart] Hogg and the Gray brothers. They are lot stronger up front than they were a few years ago. We will have to be good to win on Sunday," he said.
France: 15 Scott Spedding, 14 Wesley Fofana, 13 Gael Fickou, 12 Maxime Mermoz, 11 Virimi Vakatawa, 10 Francois Trinh-Duc, 9 Maxime Machenaud, 8 Yacouba Camara, 7 Damien Chouly, 6 Wenceslas Lauret, 5 Alexandre Flanquart, 4 Yoann Maestri, 3 Rabah Slimani, 2 Guilhem Guirado (captain), 1 Jefferson Poirot.
Replacements: 16 Camille Chat, 17 Uini Atonio, 18 Vincent Pelo, 19 Sebastien Vahaamahina, 20 Loann Goujon, 21 Sebastien Bezy, 22 Jules Plisson, 23 Maxime Medard.
