Injured Tuilagi out of Australia Tour
Tuilagi, 25, suffered the injury during Leicester's Premiership semifinal defeat against Saracens on Saturday.
Following a scan on Monday and a review by the England medical team, it was advised that Tuilagi would be unavailable for the three-Test tour in June.
"It’s bad luck for Manu so close to the tour but it provides a great opportunity for someone else," said England head coach Eddie Jones.
"We wish Manu all the best and a quick recovery."
A replacement for Tuilagi will be announced following the game against Wales on Sunday, May 29.
England squad for Australia:
Forwards: Dan Cole, Luke Cowan-Dickie, Jack Clifford, Ellis Genge, Jamie George, Teimana Harrison, Dylan Hartley, James Haskell, Paul Hill, Maro Itoje, George Kruis, Joe Launchbury, Courtney Lawes, Matt Mullan, Chris Robshaw, Kyle Sinckler, Billy Vunipola, Mako Vunipola.
Backs: Mike Brown, Danny Care, Elliot Daly, Owen Farrell, George Ford, Alex Goode, Jonathan Joseph, Jack Nowell, Henry Slade, Ben Te'o, Anthony Watson, Marland Yarde, Ben Youngs, TBC.
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