Northampton Saints and Bath have the best home records in the Premiership this season, and will fittingly host the semifinals.
The defending champion Saints lost just one match at Franklin's Gardens this season, while Bath's only defeat at the Recreation Ground was against Northampton who took top place on the standings.
Northampton will be up against Saracens, who secured their semifinal place with a resounding victory over the winless London Welsh last week.
It is Saracens' sixth successive semifinal, while for the Saints it will be number seven in a row.
Bath are up against Leicester Tigers who beat a depleted Northampton team in their East Midlands derby last week.
The home side have won their last six consecutive matches, so they will go into this one full of confidence as they seek to make their first final since 2004.
We take a closer look at both games:
Defending Premiership champions Northampton Saints have reached a sixth successive semifinal, three of which have been at home.
The Saints were defeated 14-22 at Leicester last Saturday but have not lost successive matches in the tournament for 13 months.
Northampton are the second best home side in the Premiership having equalled Bath in obtaining 47 league points from their 11 encounters. The Saints only loss at Franklin's Gardens in their last 14 games was to Exeter in November. This is Northampton's seventh Premiership semifinal, losing the first five but winning the last two, at Saracens and at home to Leicester.
Saracens have also reached a sixth successive Premiership semifinal with their 68-17 victory over London Welsh on Saturday ending a sequence of two successive losses in the tournament.
Saracens record in previous Premiership semifinals is an even won three, lost three, whilst these two foes have met in seven previous semifinals in all tournaments over the years, with the Saints having a slight edge by four wins to three, although Saracens knocked Northampton out of the Anglo-Welsh Cup at this stage in March.
The Saints have won their last three Premiership matches against Saracens whilst the Londoner's only victory in their last six encounters with the East Midlanders was 28-24 at Allianz Park in April 2014.
Recent results:
2015: Northampton won 25-20, Stadium MK
2014: Northampton won 31-24, Allianz Park
2014: Northampton won 24-20, Twickenham
2014: Saracens won 28-24, Allianz Park
2013: Northampton won 41-20, Franklin's Gardens
2013: Northampton won 27-13, Allianz Park
Prediction: Northampton did not top the log for nothing, and although Saracens should give them a good game the Saints should come out on top by about five points.
Teams:
Northampton Saints: 15 Ahsee Tuala, 14 Ken Pisi, 13 George Pisi, 12 Luther Burrell, 11 Jamie Elliott, 10 Stephen Myler, 9 Lee Dickson, 8 Samu Manoa, 7 Calum Clark, 6 Tom Wood, 5 Christian Day, 4 Courtney Lawes, 3 Salesi Ma'afu, 2 Dylan Hartley (captain), 1 Alex Corbisiero.
Replacements: 16 Mike Haywood, 17 Alex Waller, 18 Gareth Denman, 19 Sam Dickinson, 20 Jon Fisher, 21 Kahn Fotuali'i, 22 Tom Stephenson, 23 James Wilson.
Saracens: 15 Alex Goode, 14 Chris Wyles, 13 Duncan Taylor, 12 Brad Barritt, 11 David Strettle, 10 Owen Farrell, 9 Richard Wigglesworth, 8 Billy Vunipola, 7 Jacques Burger, 6 Maro Itoje, 5 George Kruis, 4 Al Hargreaves (captain), 3 Petrus du Plessis, 2 Jamie George, 1 Mako Vunipola.
Replacements: 16 Schalk Brits, 17 Richard Barrington, 18 Juan Figallo, 19 Jim Hamilton, 20 Jackson Wray, 21 Neil de Kock, 22 Charlie Hodgson, 23 Chris Ashton.
Referee: Gregory Garner
Assistant referees: Luke Pearce, Matthew Carley
TMO: Sean Davey
The Recreation Ground becomes the tenth different venue to host a Premiership semifinal, as Bath reach their first play-off since 2010 and are hoping to play in their first Premiership Final since 2004.
Bath have won their last six Premiership matches since their 6-16 defeat at Exeter in February and have not won seven in a row since season 2009/10.
Bath have the best home record in the tournament having attained 47 league points from their eleven encounters, with their only defeat at The Rec in the competition this season coming against table topping Northampton in Round 15.
Bath have played in three previous Premiership semifinals, in successive years between 2008 and 2010, but lost them all. Bath did however beat Wasps 24-18 at Adams Park in last season's semifinal of the Challenge Cup.
Leicester Tigers have reached the play-off stages for an 11th successive season with their only reversal in the last nine rounds of the Premiership coming at Saracens in Round 19.
There have been 21 previous Premiership semifinal matches with only four being won by away sides: Leicester at Gloucester in 2008, London Irish at Harlequins in 2009, Saracens at Northampton in 2010 and Saints at Saracens in 2013. The East Midlander's only reversal in a Premiership semifinal came at this stage last season at Franklin's Gardens.
Argentine prop Marcos Ayerza insists there would be no better way for Leicester Tigers to answer their critics for the season than by securing their place in the Premiership Final and going all the way to lift the trophy.
The Tigers endured a difficult start to the campaign, suffering three defeats in their opening five games – including a record 45-0 loss at the Rec, the ground they will visit in Saturday's semifinal clash with Bath.
But a run of eight wins from their last nine Premiership matches saw Richard Cockerill's men secure their 11th consecutive top-four finish, with Ayerza playing a crucial role in the 22-14 success over Northampton Saints on the final day.
And the Argentinian loosehead, who has made 14 league appearances this season, admits there will be an added incentive when they travel to the scene of their lowest Premiership ebb.
"It has hasn't always been an easy season for us as a club with quite a few injuries and some tough results, but to finish third and make it all the way to the semifinals was huge," Ayerza said.
"I think after some questions were asked about the players and the coaches, to make it all the way this year would be a massive thing for us to do.
"It feels like some people have been waiting for us to fail, so it would be nice for the supporters and everyone at Leicester to answer those questions.
"Obviously we are very happy to have made it through and set up another big match, but we know we have not done anything yet."
Recent results: 2015: Leicester won 17-8, Welford Road
2014: Bath won 45-0, Recreation Ground
2014: 27-27 draw, Welford Road
2013: Bath won 27-20, Recreation Ground
2013: Bath won 27-26 at Recreation Ground
2012: Leicester won 17-12 at Welford Road
Prediction: Leicester have got their tails up and should provide a stern test, but Bath are on home turf and should win by about three points.
Teams:
Bath: 15 Anthony Watson, 14 Semesa Rokoduguni, 13 Jonathan Joseph, 12 Kyle Eastmond, 11 Matt Banahan, 10 George Ford, 9 Peter Stringer, 8 Leroy Houston, 7 Francois Louw, 6 Sam Burgess, 5 Dave Attwood, 4 Stuart Hooper (captain), 3 David Wilson, 2 Ross Batty, 1 Paul James.
Replacements: 16 Rob Webber, 17 Nick Auterac, 18 Henry Thomas, 19 Dominic Day, 20 Matt Garvey, 21 Carl Fearns, 22 Chris Cook, 23 Ollie Devoto.
Leicester Tigers: 15 Niall Morris, 14 Adam Thompstone, 13 Mathew Tait, 12 Christian Loamanu, 11 Vereniki Goneva, 10 Freddie Burns, 9 Ben Youngs (captain), 8 Jordan Crane, 7 Julian Salvi, 6 Ed Slater, 5 Graham Kitchener, 4 Brad Thorn, 3 Dan Cole, 2 Tom Youngs, 1 Marcos Ayerza.
Replacements: 16 Neil Briggs, 17 Michele Rizzo, 18 Fraser Balmain, 19 Sebastian De Chaves, 20 Jamie Gibson, 21 Sam Harrison, 22 Tommy Bell, 23 George Catchpole.
Referee: JP Doyle
Assistant referees: Paul Dix, Ashley Rowden
TMO: Graham Hughes
