All eyes on Goosen in Pro14 Qualifier
Springbok Johan Goosen will be starting at No.10 with Niel Marais moving to centre.
Clinton Swart will be providing cover on the bench.
Clayton Bommetjies has been named at fullback, but his inclusion is subject to a late fitness test.
Swart's participation is also subject to a late fitness test.
Meanwhile, Scarlets welcome the return of wing Tom Prydie for the clash.
Prydie makes a return to action after injuring his ankle in the Pro14 clash against Leinster in February and will be an added boost for the region as they look to secure a victory in the Championship qualifier.
The rest of the backline remain unchanged from the one that faced Dragons at the Principality last weekend.
The all-Wales front row of Rob Evans, captain Ken Owens and Samson Lee lead a strong pack that sees Lewis Rawlins and Steve Cummins line up in the second row with John Barclay making a return to the No.8 berth alongside Tadhg Beirne and James Davies.
Loosehead prop Wyn Jones also makes a return from injury and is named on the replacements bench for Saturday's clash.
Scarlets: 15 Leigh Halfpenny, 14 Tom Prydie, 13 Scott Williams, 12 Hadleigh Parkes, 11 Steffan Evans, 10 Rhys Patchell, 9 Gareth Davies, 8 John Barclay, 7 James Davies, 6 Tadhg Beirne, 5 Steven Cummins, 4 Lewis Rawlins, 3 Samson Lee, 2 Ken Owens (captain), 1 Rob Evans.
Replacements: 16 Elias Ryan, 17 Wyn Jones, 18 Werner Kruger, 19 Aaron Shingler, 20 Will Boyde, 21 Jonathan Evans, 22 Daniel Jones, 23 Steffan Hughes.
Cheetahs: 15 Clayton Bommetjies, 14 William Small-Smith, 13 Francois Venter (captain), 12 Niel Marais, 11 Sibahle Maxwane, 10 Johan Goosen, 9 Tian Meyer, 8 Uzair Cassiem, 7 Teboho Mohoje, 6 Paul Schoeman, 5 Renier Bernardo, 4 Carl Wegner, 3 Johan Coetzee, 2 Torsten van Jaarsveld, 1 Retshegofaditswe Nche.
Replacements: 16 Jacques du Toit, 17 Charles Marais, 18 Tom Botha, 19 Daniel Hugo, 20 Henco Venter, 21 Mthokozisi Mkhabela, 22 Clinton Swart, 23 Lloyd Greeff.
Date: Saturday, May 5
Venue: Parc y Scarlets, Llanelli
Kick-off: 18.35 (19.35 SA time; 17.35 GMT)
Referee: George Clancy
Assistant Referees: Frank Murphy, Mike Adamson
TMO: Olly Hodges