Wales scrumhalf out for the season
Webb suffered a knee injury before the Six Nations and did not take part in the tournament. He has now undergone surgery on the knee.
A statement from the Pro14 side reads: "Rhys pulled out of Wales' Six Nations campaign and went on to have surgery on an ongoing knee problem.
"He will be unavailable for the remainder of this season and his focus is now on getting his recovery right for next season."
He has played 154 times for the Ospreys and 31 times for Wales.
The 31-year-old is set to move to Toulon for the 2018/19 season and may well play for Wales again under an agreement struck between Toulon and the WRU.
The club also stated that hooker Sam Parry’s season may also be over.
Parry "injured a chest muscle in the Cheetahs game and is currently focused on his rehabilitation. At this stage it is not anticipated that he will take any further part in the regular playing season."
